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 Miniature organoids for quick vaccine screeningThe first coronavirus case was reported in December 2019 and by the time the first COVID-19 vaccine was approved for public use in December 2020.The testing of new vaccines on animals takes up a lot of time and also raises ethical concerns about the way animal subjects are treated during such trials.

The occurrence of these mechanisms was exploited for the discovery of high-affinity antibodies against components of the conjugate on a time scale that was significantly shorter than for typical animal immunization-based workflows. The researchers selected some rabbit fever vaccine candidates and tested the same using organoids as well as traditional mice trials.These findings strongly suggest that lab-grown organoids have the potential to emerge as a great alternative to contemporary vaccine screening methods.

 Developing a vaccine suitable for human use within one year of the outbreak was a remarkable achievement.there is no doubt many many more lives couldve been saved if we had a faster vaccine screening process.

Study Abstract: Glycoengineered bacteria have emerged as a cost-effective platform for rapid and controllable biosynthesis of designer conjugate vaccines.

a sub-anatomical microenvironment that converts naıvë B cells into antibody-secreting plasma cells.they will be able to create efficient strategies to stop or at least restrict growth at the negative pole.

but do dendrites grow from the negative to the positive pole or the other way around? Or do they sprout from either pole equally? Or are there specific locations within the battery that promote nucleation and subsequent dendritic growth?Paying attention to “grain limits”The team led by Rüdiger Berger paid close attention to what is known as “grain limits” in the ceramic solid electrolyte.we propose a mechanistic model to explain the preferential growth of lithium dendrites at grain boundaries and their penetration in inorganic solid electrolytes.

Fully made of solid material and simple to miniaturizeSo-called “solid-state batteries might offer a solution.Researchers at the Max Planck Institute for Polymer Research have focused on the life cycle of solid-state batteries.